Jun 30 Wed 2021
| 1:15 PM | ||||
| 951 | Arizona DiamondbacksR. Smith -R | +166 | O 9 -110 | |
| 952 | St. Louis CardinalsK. Kim -L | -180 | U 9 -110 |
| 3:10 PM | ||||
| 955 | Pittsburgh PiratesC. Kuhl -R | +133 | O 11½ -120 | |
| 956 | Colorado RockiesJ. Gray -R | -144 | U 11½ +100 |
| 4:05 PM | ||||
| 977 | Tampa Bay RaysM. Wacha -R | -110 | O 10 -110 | |
| 978 | Washington NationalsJ. Lester -L | +100 | U 10 -110 |
| 7:05 PM | ||||
| 963 | Los Angeles AngelsS. Ohtani -R | +115 | O 9½ -110 | |
| 964 | New York YankeesD. German -R | -125 | U 9½ -110 |
| 7:07 PM | ||||
| 965 | Seattle MarinersJ. Sheffield -L | +166 | O 10½ -110 | |
| 966 | Toronto Blue JaysS. Matz -L | -180 | U 10½ -110 |
| 7:10 PM | ||||
| 959 | San Diego PadresJ. Musgrove -R | -160 | O 10 +105 | |
| 960 | Cincinnati RedsV. Gutierrez -R | +148 | U 10 -125 |
| 7:10 PM | ||||
| 967 | Detroit TigersW. Peralta -R | +165 | O 10 -115 | |
| 968 | Cleveland IndiansC. Quantrill -R | -179 | U 10 -105 |
| 7:10 PM | ||||
| 969 | Kansas City RoyalsM. Minor -L | +148 | O 10½ -120 | |
| 970 | Boston Red SoxM. Perez -L | -160 | U 10½ +100 |
| 7:20 PM | ||||
| 961 | New York MetsD. Peterson -L | +139 | O 8½ -115 | |
| 962 | Atlanta BravesM. Fried -L | -150 | U 8½ -105 |
| 8:10 PM | ||||
| 971 | Minnesota TwinsB. Ober -R | +125 | O 9 +100 | |
| 972 | Chicago White SoxD. Cease -R | -135 | U 9 -120 |
| 8:10 PM | ||||
| 973 | Baltimore OriolesM. Harvey -R | +266 | O 10 -105 | |
| 974 | Houston AstrosL. Garcia -R | -300 | U 10 -115 |
| 9:40 PM | ||||
| 975 | Texas RangersK. Allard -L | +175 | O 8 +100 | |
| 976 | Oakland AthleticsC. Bassitt -R | -190 | U 8 -120 |
