Aug 31 Tue 2021
| 5:40 PM | ||||
| 901 | St. Louis CardinalsM. Mikolas -R | +1½ -150 | +132 | O 9 -110 |
| 902 | Cincinnati RedsS. Gray -R | -1½ +130 | -143 | U 9 -110 |
| 6:05 PM | ||||
| 903 | Philadelphia PhilliesM. Moore -L | -1½ +140 | -102 | O 9 -115 |
| 904 | Washington NationalsP. Corbin -L | +1½ -160 | -108 | U 9 -105 |
| 6:07 PM | ||||
| 913 | Baltimore OriolesK. Akin -L | +1½ +150 | +292 | O 9½ -115 |
| 914 | Toronto Blue JaysH. Ryu -L | -1½ -170 | -330 | U 9½ -105 |
| 6:10 PM | ||||
| 915 | Oakland AthleticsC. Irvin -L | -1½ +130 | -118 | O 9 -120 |
| 916 | Detroit TigersT. Skubal -L | +1½ -150 | +108 | U 9 +100 |
| 7:05 PM | ||||
| 925 | Colorado RockiesA. Gomber -L | -1½ +115 | -133 | O 9 +105 |
| 926 | Texas RangersJ. Lyles -R | +1½ -135 | +123 | U 9 -125 |
| 7:10 PM | ||||
| 927 | Pittsburgh PiratesB. Wilson -R | +1½ +125 | +249 | O 9 +105 |
| 928 | Chicago White SoxL. Giolito -R | -1½ -145 | -280 | U 9 -125 |
| 7:10 PM | ||||
| 929 | Chicago CubsZ. Davies -R | +1½ -135 | +139 | O 9½ -115 |
| 930 | Minnesota TwinsJ. Gant -R | -1½ +115 | -150 | U 9½ -105 |
| 8:40 PM | ||||
| 907 | San Diego PadresB. Snell -L | -1½ -105 | -160 | O 9 +105 |
| 908 | Arizona DiamondbacksZ. Gallen -R | +1½ -115 | +148 | U 9 -125 |
| 9:10 PM | ||||
| 911 | Atlanta BravesC. Morton -R | +1½ -140 | +154 | O 8 -122 |
| 912 | Los Angeles DodgersW. Buehler -R | -1½ +120 | -167 | U 8 +102 |
| 9:10 PM | ||||
| 923 | Houston AstrosL. McCullers Jr. -R | -1½ +105 | -150 | O 8½ +110 |
| 924 | Seattle MarinersY. Kikuchi -L | +1½ -125 | +139 | U 8½ -130 |
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