Jul 18 Sun 2021
| 1:05 PM | ||||
| 903 | San Diego PadresJ. Musgrove -R | -105 | O 8 -110 | |
| 904 | Washington NationalsM. Scherzer -R | -105 | U 8 -110 |
| 1:05 PM | ||||
| 905 | Miami MarlinsP. Lopez -R | +130 | O 7½ -110 | |
| 906 | Philadelphia PhilliesZ. Wheeler -R | -140 | U 7½ -110 |
| 1:07 PM | ||||
| 931 | Texas Rangers - Game #1K. Allard -L | +212 | O 7½ -115 | |
| 932 | Toronto Blue Jays - Game #1 H. Ryu -L | -235 | U 7½ -105 |
| 1:10 PM | ||||
| 907 | Milwaukee BrewersC. Burnes -R | -125 | O 8 -120 | |
| 908 | Cincinnati RedsS. Gray -R | +115 | U 8 +100 |
| 1:10 PM | ||||
| 917 | Minnesota TwinsJ. Happ -L | -125 | O 10 -110 | |
| 918 | Detroit TigersW. Peralta -R | +115 | U 10 -110 |
| 1:20 PM | ||||
| 929 | Tampa Bay RaysR. Hill -L | -105 | O 9 -105 | |
| 930 | Atlanta BravesD. Smyly -L | -105 | U 9 -115 |
| 2:10 PM | ||||
| 919 | Houston AstrosF. Valdez -L | -105 | O 8½ -105 | |
| 920 | Chicago White SoxC. Rodon -L | -105 | U 8½ -115 |
| 2:15 PM | ||||
| 909 | San Francisco GiantsJ. Cueto -R | -111 | O 8½ -120 | |
| 910 | St. Louis CardinalsW. Leblanc -L | +101 | U 8½ +100 |
| 3:10 PM | ||||
| 911 | Los Angeles DodgersD. Price -L | -177 | O 12 -110 | |
| 912 | Colorado RockiesJ. Gray -R | +163 | U 12 -110 |
| 4:07 PM | ||||
| 923 | Seattle MarinersL. Gilbert -R | +113 | O 9 +110 | |
| 924 | Los Angeles AngelsP. Sandoval -L | -123 | U 9 -130 |
| 4:07 PM | ||||
| 925 | Cleveland IndiansZ. Plesac -R | +150 | O 8½ -105 | |
| 926 | Oakland AthleticsC. Bassitt -R | -163 | U 8½ -115 |
| 4:07 PM | ||||
| 933 | Texas Rangers - Game #2M. Foltynewicz -R | +172 | O 8½ +100 | |
| 934 | Toronto Blue Jays - Game #2 S. Matz -L | -187 | U 8½ -120 |
| 4:10 PM | ||||
| 913 | Chicago CubsZ. Davies -R | -114 | O 9 -120 | |
| 914 | Arizona DiamondbacksM. Kelly -R | +104 | U 9 +100 |
| 7:08 PM | ||||
| 927 | Boston Red SoxM. Perez -L | -101 | O 9 -120 | |
| 928 | New York YankeesJ. Tallion -R | -109 | U 9 +100 |
