Sep 3 Fri 2021
| 6:05 PM | ||||
| 953 | New York MetsR. Hill -L | -1½ +112 | -133 | O 9 -117 |
| 954 | Washington NationalsS. Nolin -L+5 Markets | +1½ -132 | +123 | U 9 -103 |
| 6:05 PM | ||||
| 963 | Baltimore OriolesJ. Means -L | +1½ +100 | +204 | O 9 -117 |
| 964 | New York YankeesN. Cortes -L+5 Markets | -1½ -120 | -225 | U 9 -103 |
| 6:07 PM | ||||
| 965 | Oakland AthleticsS. Manaea -L | +1½ -145 | +140 | O 8½ -118 |
| 966 | Toronto Blue JaysA. Manoah -R+5 Markets | -1½ +125 | -152 | U 8½ -102 |
| 6:10 PM | ||||
| 955 | Philadelphia PhilliesK. Gibson -R | -1½ +120 | -139 | O 7½ -117 |
| 956 | Miami MarlinsJ. Luzardo -L+5 Markets | +1½ -140 | +129 | U 7½ -103 |
| 6:10 PM | ||||
| 967 | Minnesota TwinsR. Dobnak -R | +1½ -113 | +174 | O 9 -110 |
| 968 | Tampa Bay RaysM. Wacha -R+5 Markets | -1½ -107 | -189 | U 9 -110 |
| 6:10 PM | ||||
| 969 | Cleveland IndiansC. Quantrill -R | +1½ -125 | +154 | O 9 -101 |
| 970 | Boston Red SoxN. Eovaldi -R+5 Markets | -1½ +105 | -167 | U 9 -119 |
| 6:10 PM | ||||
| 975 | Detroit TigersT. Alexander -L | +1½ -125 | +161 | O 9½ -105 |
| 976 | Cincinnati RedsV. Gutierrez -R+5 Markets | -1½ +105 | -175 | U 9½ -115 |
| 7:10 PM | ||||
| 957 | St. Louis CardinalsA. Wainwright -R | +1½ -145 | +157 | O 7½ +100 |
| 958 | Milwaukee BrewersF. Peralta -R+5 Markets | -1½ +125 | -171 | U 7½ -120 |
| 7:10 PM | ||||
| 971 | Chicago White SoxD. Keuchel -L | -1½ +120 | -121 | O 9 -125 |
| 972 | Kansas City RoyalsC. Hernandez -R+5 Markets | +1½ -140 | +111 | U 9 +105 |
| 7:40 PM | ||||
| 959 | Atlanta BravesH. Ynoa -R | -1½ +107 | -131 | O 11 -115 |
| 960 | Colorado RockiesA. Senzatela -R+5 Markets | +1½ -127 | +121 | U 11 -105 |
| 8:38 PM | ||||
| 973 | Texas RangersG. Otto -R | +1½ -126 | +167 | O 7½ -119 |
| 974 | Los Angeles AngelsS. Ohtani -R+5 Markets | -1½ +106 | -182 | U 7½ -101 |
| 8:40 PM | ||||
| 977 | Seattle MarinersT. Anderson -L | -1½ +140 | -110 | O 8½ -118 |
| 978 | Arizona DiamondbacksM. Bumgarner -L+5 Markets | +1½ -160 | +100 | U 8½ -102 |
| 8:45 PM | ||||
| 961 | Los Angeles DodgersD. Price -L | -1½ +138 | -114 | O 8½ -118 |
| 962 | San Francisco GiantsA. Desclafani -R+5 Markets | +1½ -158 | +104 | U 8½ -102 |
| 9:10 PM | ||||
| 979 | Houston AstrosJ. Urquidy -R | -1½ +117 | -130 | O 9 -119 |
| 980 | San Diego PadresJ. Arrieta -R+5 Markets | +1½ -137 | +120 | U 9 -101 |
