Jul 17 Sat 2021
| 3:07 PM | ||||
| 965 | Texas RangersK. Allard -L | +212 | O 9½ +105 | |
| 966 | Toronto Blue JaysH. Ryu -L | -235 | U 9½ -125 |
| 6:05 PM | ||||
| 951 | Miami MarlinsZ. Thompson -R | +120 | O 9 +100 | |
| 952 | Philadelphia PhilliesV. Velasquez -R | -130 | U 9 -120 |
| 7:05 PM | ||||
| 953 | San Diego PadresB. Snell -L | -120 | O 9 -125 | |
| 954 | Washington NationalsP. Corbin -L | +110 | U 9 +105 |
| 7:05 PM | ||||
| 955 | New York MetsT. Megill -R | -171 | O 8½ -125 | |
| 956 | Pittsburgh PiratesW. Crowe -R | +157 | U 8½ +105 |
| 7:10 PM | ||||
| 957 | Milwaukee BrewersB. Woodruff -R | -110 | O 7½ -110 | |
| 958 | Cincinnati RedsL. Castillo -R | +100 | U 7½ -110 |
| 7:15 PM | ||||
| 959 | San Francisco GiantsA. Desclafani -R | -117 | O 7½ -110 | |
| 960 | St. Louis CardinalsK. Kim -L | +107 | U 7½ -110 |
| 7:15 PM | ||||
| 973 | Houston AstrosJ. Odorizzi -R | -102 | O 8½ -110 | |
| 974 | Chicago White SoxL. Giolito -R | -108 | U 8½ -110 |
| 7:20 PM | ||||
| 979 | Tampa Bay RaysJ. Fleming -L | +110 | O 8½ -110 | |
| 980 | Atlanta BravesM. Fried -L | -120 | U 8½ -110 |
| 8:10 PM | ||||
| 963 | Los Angeles DodgersW. Buehler -R | -230 | O 11½ -110 | |
| 964 | Colorado RockiesC. Gonzalez -R | +208 | U 11½ -110 |
| 9:07 PM | ||||
| 977 | Seattle MarinersY. Kikuchi -L | +120 | O 9 +105 | |
| 978 | Los Angeles AngelsA. Cobb -R | -130 | U 9 -125 |
