Jun 19 Sat 2021
| 1:05 PM | ||||
| 917 | Oakland AthleticsC. Bassitt -R | +115 | O 9 -110 | |
| 918 | New York YankeesD. German -R | -125 | U 9 -110 |
| 4:05 PM | ||||
| 905 | Philadelphia PhilliesA. Nola -R | -105 | O 8 +105 | |
| 906 | San Francisco GiantsA. Wood -L | -105 | U 8 -125 |
| 4:05 PM | ||||
| 921 | Toronto Blue JaysA. Manoah -R | -165 | O 10 +100 | |
| 922 | Baltimore OriolesD. Kremer -R | +152 | U 10 -120 |
| 4:05 PM | ||||
| 931 | Cleveland IndiansC. Quantrill -R | -135 | O 9 -110 | |
| 932 | Pittsburgh PiratesW. Crowe -R | +125 | U 9 -110 |
| 4:10 PM | ||||
| 923 | Boston Red SoxM. Perez -L | -125 | O 10½ -115 | |
| 924 | Kansas City RoyalsK. Bubic -L | +115 | U 10½ -105 |
| 7:15 PM | ||||
| 909 | Cincinnati RedsV. Gutierrez -R | +166 | O 8½ -110 | |
| 910 | San Diego PadresD. Lamet -R | -180 | U 8½ -110 |
| 7:15 PM | ||||
| 911 | St. Louis CardinalsA. Wainwright -R | +110 | O 9½ -110 | |
| 912 | Atlanta BravesD. Smyly -L | -120 | U 9½ -110 |
| 7:15 PM | ||||
| 925 | Chicago White SoxL. Lynn -R | +115 | O 8 -105 | |
| 926 | Houston AstrosF. Valdez -L | -125 | U 8 -115 |
| 9:10 PM | ||||
| 913 | Milwaukee BrewersA. Houser -R | -125 | O 11 +100 | |
| 914 | Colorado RockiesA. Gomber -L | +115 | U 11 -120 |
| 10:07 PM | ||||
| 927 | Detroit TigersW. Peralta -R | +175 | O 9 -130 | |
| 928 | Los Angeles AngelsP. Sandoval -L | -190 | U 9 +110 |
| 10:10 PM | ||||
| 915 | Los Angeles DodgersW. Buehler -R | -205 | O 9 -120 | |
| 916 | Arizona DiamondbacksM. Peacock -R | +188 | U 9 +100 |
| 10:10 PM | ||||
| 929 | Tampa Bay RaysJ. Fleming -L | -125 | O 8 -110 | |
| 930 | Seattle MarinersL. Gilbert -R | +115 | U 8 -110 |
