Jun 12 Sat 2021
| 4:05 PM | ||||
| 975 | New York YankeesJ. Tallion -R | -125 | O 9½ -110 | |
| 976 | Philadelphia PhilliesV. Velasquez -R | +115 | U 9½ -110 |
| 4:07 PM | ||||
| 963 | Kansas City RoyalsJ. Kowar -R | +130 | O 8½ -120 | |
| 964 | Oakland AthleticsJ. Kaprielian -R+1 Markets | -141 | U 8½ +100 |
| 4:10 PM | ||||
| 951 | Colorado RockiesG. Marquez -R | +125 | O 9 -115 | |
| 952 | Cincinnati RedsW. Miley -L+1 Markets | -135 | U 9 -105 |
| 4:10 PM | ||||
| 953 | Pittsburgh PiratesC. Kuhl -R | +241 | O 7½ -115 | |
| 954 | Milwaukee BrewersC. Burnes -R+1 Markets | -270 | U 7½ -105 |
| 4:10 PM | ||||
| 957 | San Diego PadresJ. Musgrove -R | -120 | O 7½ +105 | |
| 958 | New York MetsM. Stroman -R+1 Markets | +110 | U 7½ -125 |
| 4:10 PM | ||||
| 965 | Chicago White SoxD. Cease -R | -165 | O 9 +100 | |
| 966 | Detroit TigersJ. Urena -R+1 Markets | +152 | U 9 -120 |
| 4:10 PM | ||||
| 967 | Toronto Blue JaysS. Matz -L | +110 | O 10 -115 | |
| 968 | Boston Red SoxN. Pivetta -R+1 Markets | -120 | U 10 -105 |
| 7:15 PM | ||||
| 973 | Houston AstrosL. Garcia -R | -105 | O 9½ -105 | |
| 974 | Minnesota TwinsJ. Berrios -R+1 Markets | -105 | U 9½ -115 |
| 10:10 PM | ||||
| 979 | Texas RangersK. Allard -L | +258 | O 7½ -115 | |
| 980 | Los Angeles DodgersT. Bauer -R+1 Markets | -290 | U 7½ -105 |
