Aug 13 Fri 2021
| 7:05 PM | ||||
| 901 | Cincinnati RedsT. Mahle -R | +149 | O 8½ -120 | |
| 902 | Philadelphia PhilliesZ. Wheeler -R | -162 | U 8½ +100 |
| 7:05 PM | ||||
| 903 | Milwaukee BrewersB. Anderson -L | -177 | O 9 -125 | |
| 904 | Pittsburgh PiratesM. Keller -R | +163 | U 9 +105 |
| 7:10 PM | ||||
| 907 | Chicago CubsA. Alzolay -R | +108 | O 8 -120 | |
| 908 | Miami MarlinsJ. Luzardo -L | -118 | U 8 +100 |
| 7:10 PM | ||||
| 909 | Los Angeles DodgersJ. Urias -L | -143 | O 9 +100 | |
| 910 | New York MetsT. Megill -R | +132 | U 9 -120 |
| 7:10 PM | ||||
| 915 | Cleveland IndiansZ. Plesac -R | -112 | O 9½ -115 | |
| 916 | Detroit TigersT. Alexander -L | +102 | U 9½ -105 |
| 7:10 PM | ||||
| 917 | Baltimore OriolesS. Watkins -R | +216 | O 11 -115 | |
| 918 | Boston Red SoxN. Pivetta -R | -240 | U 11 -105 |
| 8:05 PM | ||||
| 919 | Oakland AthleticsC. Irvin -L | -171 | O 8½ +100 | |
| 920 | Texas RangersD. Dunning -R | +157 | U 8½ -120 |
| 8:10 PM | ||||
| 921 | Tampa Bay RaysS. McClanahan -L | -157 | O 9½ -110 | |
| 922 | Minnesota TwinsM. Pineda -R | +145 | U 9½ -110 |
| 8:10 PM | ||||
| 927 | St. Louis CardinalsJ. Flaherty -R | -128 | O 9 -120 | |
| 928 | Kansas City RoyalsM. Minor -L | +118 | U 9 +100 |
| 9:40 PM | ||||
| 911 | San Diego PadresB. Snell -L | -166 | O 9 +105 | |
| 912 | Arizona DiamondbacksM. Bumgarner -L | +153 | U 9 -125 |
| 9:45 PM | ||||
| 913 | Colorado RockiesA. Gomber -L | +188 | O 8 +100 | |
| 914 | San Francisco GiantsA. Desclafani -R | -205 | U 8 -120 |
