| 12:00 PM | Texas @ 16 Baylor | ABC | Joe Tessitore, Greg McElroy |
| 12:00 PM | 6 Michigan @ 8 Michigan State | FOX | Gus Johnson, Joel Klatt |
| 12:00 PM | 9 Iowa @ Wisconsin | ESPN | Bob Wischusen, Dan Orlovsky |
| 12:00 PM | 2 Cincinnati @ Tulane | ESPN2 | Anish Shroff, Mike Golic Jr. |
| 12:00 PM | Texas State @ Louisiana | ESPNU | Kevin Brown, Hutson Mason |
| 12:00 PM | Indiana @ Maryland | BTN | Chris Vosters, Matt Millen |
| 12:00 PM | Rutgers @ Illinois | BTN | Jeff Levering, Anthony Herron |
| 12:00 PM | Miami @ 17 Pittsburgh | ACCN | Chris Cotter, Mark Herzlich |
| 12:00 PM | Bowling Green @ Buffalo | CBSSN | Jason Knapp, Ross Tucker |
| 12:00 PM | Virginia Tech @ Georgia Tech | ACC RSNs | Tom Werme, James Bates |
| 12:00 PM | Central Florida @ Temple | ESPN+ | Richard Cross, Leger Douzable |
| 2:00 PM | 22 Iowa State @ West Virginia | ESPN+ | Courtney Lyle, Brandon Weeden |
| 2:00 PM | North Texas @ Rice | ESPN3 | |
| 3:00 PM | Washington State @ Arizona State | FS1 | Cory Provus, Mark Helfrich |
| 3:00 PM | Missouri @ Vanderbilt | SECN | Dave Neal, Deuce McAllister |
| 3:00 PM | Hawaii @ Utah State | Hawaii PPV,
Team1Sports | |
| 3:30 PM | Texas Tech @ 4 Oklahoma | ABC | Dave Pasch, Dusty Dvoracek, Tom Luginbill |
| 3:30 PM | Florida vs 1 Georgia
(in Jacksonville) | CBS | Brad Nessler, Gary Danielson |
| 3:30 PM | Colorado @ 7 Oregon | FOX | Aaron Goldsmith, Brock Huard |
| 3:30 PM | Florida State @ Clemson | ESPN | Asshole Mark Jones, Robert Griffin III, Quint Kessenich |
| 3:30 PM | Purdue @ Nebraska | ESPN2 | Roy Philpott, Kelly Stouffer |
| 3:30 PM | TCU @ Kansas State | ESPNU | Mike Couzens, Dustin Fox |
| 3:30 PM | Minnesota @ Northwestern | BTN | Brandon Gaudin, James Laurinaitis |
| 3:30 PM | Louisiana Tech @ Old Dominion | CBSSN | Chris Hassel, Sed Bonner |
| 3:30 PM | Boston College @ Syracuse | ACC RSNs | Evan Lepler, Charles Arbuckle |
| 3:30 PM | Florida International @ Marshall | Stadium | |
| 3:30 PM | ULM @ Appalachian State | ESPN+ | |
| 3:30 PM | Southern Mississippi @ Middle Tennessee | ESPN+ | |
| 4:00 PM | Wyoming @ San Jose State | FS2 | Eric Collins, Devin Gardner |
| 4:00 PM | Duke @ 13 Wake Forest | ACCN | Wes Durham, Roddy Jones |
| 4:00 PM | Charlotte @ Western Kentucky | ESPN+ | |
| 5:00 PM | Arkansas State @ South Alabama | ESPN+ | |
| 6:00 PM | Georgia State @ Georgia Southern | ESPN+ | |
| 6:00 PM | UTEP @ Florida Atlantic | ESPN+ | |
| 7:00 PM | 10 Ole Miss @ 18 Auburn | ESPN | Sean McDonough, Todd Blackledge |
| 7:00 PM | 19 Southern Methodist @ Houston | ESPN2 | Taylor Zarzour, Matt Stinchcomb |
| 7:00 PM | Kansas @ 15 Oklahoma State | FS1 | Tim Brando, Spencer Tillman |
| 7:00 PM | Arizona @ USC | ESPNU | John Schriffen, Rene Ingoglia |
| 7:00 PM | 12 Kentucky @ Mississippi State | SECN | Tom Hart, Jordan Rodgers, Cole Cubelic |
| 7:00 PM | Boise State @ Colorado State | CBSSN | Rich Waltz, Aaron Taylor |
| 7:30 PM | 20 Penn State @ 5 Ohio State | ABC | Chris Fowler, Kirk Herbstreit |
| 7:30 PM | North Carolina @ 11 Notre Dame | NBC | Mike Tirico, Drew Brees |
| 7:30 PM | Oregon State @ California | P12N | Ted Robinson, Yogi Roth |
| 7:30 PM | Louisville @ N.C. State | ACCN | Dave O'Brien, Tim Hasselbeck |
| 10:00 PM | UCLA @ Utah | ESPN | Dave Flemming, Asshole Rod Gilmore |
| 10:15 PM | Virginia @ 25 BYU | ESPN2 | Beth Mowins, Kirk Morrison |
| 10:30 PM | Washington @ Stanford | FS1 | Alex Faust, Petros Papadakis |
| 10:30 PM | Fresno State @ 21 San Diego State | CBSSN | Dave Ryan, Aaron Murray |
