| 12:00 PM | 4 Clemson @ Florida State | ABC | Dave Pasch, Mike Golic |
| 12:00 PM | 9 Indiana @ 3 Ohio State | FOX | Gus Johnson, Joel Klatt |
| 12:00 PM | 6 Florida @ Vanderbilt | ESPN | Bob Wischusen, Dan Orlovsky |
| 12:00 PM | Appalachian State @ 15 Coastal Carolina | ESPN2 | Clay Matvick, Dustin Fox |
| 12:00 PM | Illinois @ Nebraska | FS1 | Brian Custer, Robert Smith |
| 12:00 PM | Arkansas State @ Texas State | ESPNU | Brant Freeman, Steve Foster |
| 12:00 PM | LSU @ Arkansas | SECN | Taylor Zarzour, Matt Stinchcomb |
| 12:00 PM | Georgia Southern @ Army | CBSSN | Ben Holden, Ross Tucker |
| 12:00 PM | Stephen F. Austin @ Memphis | ESPN+ | David Saltzman, Keith Moreland |
| 12:00 PM | East Carolina @ Temple | ESPN+ | Dave Leno, Ken Dunek |
| 2:00 PM | Rice @ North Texas | ESPN3 | |
| 2:00 PM | Florida International @ Western Kentucky | ESPN3 | |
| 3:00 PM | North Alabama @ 8 BYU | BYU TV | Dave McCann, Blaine Fowler |
| 3:00 PM | UTSA @ Southern Mississippi | ESPN+ | |
| 3:30 PM | 10 Wisconsin @ 19 Northwestern | ABC | Sean McDonough, Todd Blackledge, Todd McShay |
| 3:30 PM | San Diego State @ Nevada | CBS | Brad Nessler, Gary Danielson |
| 3:30 PM | 7 Cincinnati @ UCF | ESPN | Asshole Mark Jones, Dusty Dvoracek |
| 3:30 PM | UCLA @ 11 Oregon | ESPN2 | Jason Benetti, Andre Ware |
| 3:30 PM | California @ Oregon State | FS1 | Eric Collins, Ben Leber |
| 3:30 PM | Iowa @ Penn State | BTN | Joe Beninati, Matt Millen |
| 3:30 PM | Middle Tennessee @ Troy | ESPN3 | |
| 4:00 PM | Kansas State @ 17 Iowa State | FOX | Tim Brando, Spencer Tillman |
| 4:00 PM | Georgia State @ South Alabama | ESPNU | Mike Couzens, Rocky Boiman |
| 4:00 PM | Kentucky @ 1 Alabama | SECN | Tom Hart, Jordan Rodgers, Cole Cubelic |
| 4:00 PM | Virginia Tech @ Pittsburgh | ACCN | Chris Cotter, Eric Wood |
| 4:00 PM | Abilene Christian @ Virginia | ACC RSNs | Evan Lepler, Brian Jordan |
| 7:00 PM | Tennessee @ 23 Auburn | ESPN | Joe Tessitore, Greg McElroy |
| 7:00 PM | San Jose State @ Fresno State | CBSSN | Rich Waltz, Aaron Murray |
| 7:30 PM | 14 Oklahoma State @ 18 Oklahoma | ABC | Chris Fowler, Kirk Herbstreit |
| 7:30 PM | Mississippi State @ 13 Georgia | SECN | Dave Neal, DJ Shockley |
| 7:30 PM | Missouri @ South Carolina | SECN (alt) | Mike Morgan, Hutson Mason |
| 7:30 PM | Michigan @ Rutgers | BTN | Mark Followill, James Laurinaitis |
| 7:30 PM | 21 Liberty @ N.C. State | ACC RSNs | Tom Werme, James Bates |
| 8:00 PM | Arizona @ Washington | FOX | Joe Davis, Mark Helfrich |
| 10:30 PM | 20 USC @ Utah | ESPN | Dave Flemming, Rod Gilmore |
| 10:30 PM | Washington State @ Stanford | FS1 | Alex Faust, Petros Papadakis |
| 11:00 PM | Boise State @ Hawaii | CBSSN | John Sadak, Randy Cross |
