Tennessee hosting the Giants to me seems like the play. Non-division home game. No other attractive games for them until week 8 and that's a road divisional game, yuk. You get Henry at his peak health. Who knows where the Titans will be second half of the year. Vibes for the Giants have all been pretty bad except for Barkley returning to health. Toney, Shepherd both dealing with injuries already. Golladay has been getting ripped all camp.
2nd choice is Baltimore. Harbaugh against bottom feeders Week 1 is usually easy pickings.
If you don't like those two then next tier would be Indy at Houston and New Orleans at Atlanta, but again, road divisional game. Philly at Detroit would also be on that tier but Lions might score some this year. All 3 teams have better spots in October worth holding out for.
After that the pickings look really slim unless you're looking for a bold separator pick.