Jul 5 Mon 2021
| 6:05 PM | ||||
| 901 | St. Louis CardinalsK. Kim -L | +163 | O 7 -120 | |
| 902 | San Francisco GiantsK. Gausman -R | -177 | U 7 +100 |
| 6:40 PM | ||||
| 903 | Los Angeles DodgersW. Buehler -R | -150 | O 7 -120 | |
| 904 | Miami MarlinsT. Rogers -L | +139 | U 7 +100 |
| 7:05 PM | ||||
| 905 | Atlanta BravesM. Fried -L | -181 | O 8½ +100 | |
| 906 | Pittsburgh PiratesC. De Jong -R | +166 | U 8½ -120 |
| 7:10 PM | ||||
| 907 | Milwaukee BrewersB. Woodruff -R | -164 | O 7½ -103 | |
| 908 | New York MetsT. Megill -R | +151 | U 7½ -117 |
| 7:10 PM | ||||
| 913 | Chicago White SoxD. Cease -R | -106 | O 9½ -125 | |
| 914 | Minnesota TwinsB. Ober -R | -104 | U 9½ +105 |
| 7:10 PM | ||||
| 915 | Cleveland IndiansL. Allen -L | +171 | O 8½ -125 | |
| 916 | Tampa Bay RaysR. Hill -L | -186 | U 8½ +105 |
| 8:05 PM | ||||
| 917 | Detroit TigersW. Peralta -R | +136 | O 9 -120 | |
| 918 | Texas RangersK. Allard -L | -147 | U 9 +100 |
| 8:10 PM | ||||
| 921 | Cincinnati RedsV. Gutierrez -R | +108 | O 10 +100 | |
| 922 | Kansas City RoyalsM. Minor -L | -118 | U 10 -120 |
| 9:38 PM | ||||
| 919 | Boston Red SoxM. Perez -L | -103 | O 10 -105 | |
| 920 | Los Angeles AngelsJ. Suarez -L | -107 | U 10 -115 |
| 10:10 PM | ||||
| 911 | Washington NationalsJ. Lester -L | +192 | O 8 +100 | |
| 912 | San Diego PadresJ. Musgrove -R | -210 | U 8 -120 |
