Jul 2 Fri 2021
| 7:05 PM | ||||
| 953 | Milwaukee BrewersA. Houser -R | -152 | O 8½ -105 | |
| 954 | Pittsburgh PiratesJ. Brubaker -R | +140 | U 8½ -115 |
| 7:05 PM | ||||
| 955 | Los Angeles DodgersJ. Urias -L | +105 | O 8 +100 | |
| 956 | Washington NationalsM. Scherzer -R | -115 | U 8 -120 |
| 7:05 PM | ||||
| 979 | New York MetsT. Walker -R | +121 | O 9 -120 | |
| 980 | New York YankeesJ. Montgomery -L | -131 | U 9 +100 |
| 7:10 PM | ||||
| 957 | Chicago CubsA. Mills -R | +141 | O 9½ -120 | |
| 958 | Cincinnati RedsS. Gray -R | -153 | U 9½ +100 |
| 7:10 PM | ||||
| 967 | Houston AstrosL. McCullers Jr. -R | -172 | O 9½ +100 | |
| 968 | Cleveland IndiansS. Hentges -L | +158 | U 9½ -120 |
| 7:10 PM | ||||
| 969 | Chicago White SoxL. Lynn -R | -156 | O 8 -115 | |
| 970 | Detroit TigersC. Mize -R | +144 | U 8 -105 |
| 8:10 PM | ||||
| 961 | St. Louis CardinalsJ. Oviedo -R | -112 | O 12 +105 | |
| 962 | Colorado RockiesC. Gonzalez -R | +102 | U 12 -125 |
| 8:10 PM | ||||
| 971 | Minnesota TwinsJ. Happ -L | -103 | O 10 -120 | |
| 972 | Kansas City RoyalsB. Singer -R | -107 | U 10 +100 |
| 9:38 PM | ||||
| 973 | Baltimore OriolesK. Akin -L | +154 | O 9½ +100 | |
| 974 | Los Angeles AngelsG. Canning -R | -167 | U 9½ -120 |
| 9:40 PM | ||||
| 963 | San Francisco GiantsA. Wood -L | -132 | O 8½ -120 | |
| 964 | Arizona DiamondbacksZ. Gallen -R | +122 | U 8½ +100 |
| 9:40 PM | ||||
| 975 | Boston Red SoxE. Rodriguez -L | +106 | O 8½ -105 | |
| 976 | Oakland AthleticsF. Montas -R | -116 | U 8½ -115 |
| 10:10 PM | ||||
| 977 | Texas RangersK. Gibson -R | -110 | O 8 +100 | |
| 978 | Seattle MarinersL. Gilbert -R | +100 | U 8 -120 |
